Nk Cell Therapy Clinical Trials

Billionaire controlled biotech ind approved for nk cell therapy to enter clinical trials jun 24 2019 cancer car t oncology pd l1 nantkwest launches the first engineered gmp grade cryopreserved off the shelf bi specific nk cell therapy to enter human clinical trials targeting pd l1 and cd16 in patients with solid tumors.

Nk cell therapy clinical trials.

Actual study completion date. 1 chiossone l et al natural killer cells and other innate lymphoid cells in cancer. Actual study start date. It has been used for cancer treatments.

Determine antitumor activity of allogeneic nk cells with alt 803 support. Currently therefore access to our investigational cell therapy is limited to patients meeting the eligibility criteria of our clinical trials. Actual primary completion date. Similar to the recently approved car t cell therapy the new clinical trial would add car to natural killer cells also called nk cells.

On day 0 all patients will receive a fixed dose of 1 0 3 0 x 10 9 allogeneic umbilical cord blood derived nk cells ucb nk cells. Natural killer nk cells are innate lymphocytes that may serve as useful effectors against danger infection. K nk002 a phase 2 study nct04395092 evaluating haplo identical nk cells to prevent post transplant relapse in aml and mds. To determine the maximum tolerated dose of ex vivo expanded non hla matched donor nk cells in combination with alt 803.

Phase 1 clinical trial to evaluate the safety of allogeneic nk cell smt nk cell therapy in advanced biliary tract cancer. Describe safety profile toxicity of combining alt 803 with nk cell adoptive therapy. Just when it looked like jc options were again dwindling a new clinical trial testing car nk therapy was launching at md anderson. The purpose of this clinical investigation is to evaluate the safety and efficiency of nk cells in combination with standard therapy for pneumonia patients infected with 2019 ncov.

The clinical trials on this list are studying allogeneic natural killer cell line nk 92. Nci s basic information about clinical trials explains the types and phases of trials and how they are carried out. Prior to nk cell infusion all patients will receive cyclophosphamide and fludarabine cy flu based lymphodepleting chemotherapy. All trials on the list are supported by nci.

Car nk cell therapy clinical trial offers hope.