Nci Human Tumor Cell Line Database

Nci 60 human tumor cell lines screen introduction.

Nci human tumor cell line database.

Additional lines evaluated for use in the screen and currently available are listed separately at the bottom of the page. Compounds are identified by the nci nsc number. Compounds are identified by the nci nsc number. Activity score was based on increasing values of loggi50.

Cell lines in the in vitro screen. Basically compounds with loggi50 unit m less than 6 were considered as active. In the nci numbering system nci h23 is panel number 1 cell number 1. In the nci numbering system a498 is panel number 9 cell number 13.

The nci 60 cell lines used by nci s human tumor cell lines screen as described on the website of the developmental therapeutics program. The database also contains microarray assay gene expression data for the cell lines and so it provides an excellent information resource particularly for testing data mining methods. The screen was implemented in fully operational form in 1990 and utilizes 60 different human tumor cell lines to identify and characterize novel compounds with growth inhibition or killing of tumor cell lines. The nci developmental therapeutics program human tumor cell line data set is a publicly available database that contains cellular assay screening data for over 40 000 compounds tested in 60 human tumor cell lines.

The nci 60 human tumor cell lines screen has served the global cancer research community for 20 years. The cellosaurus identifier is a combination of the cell line name variant chosen by cellosaurus with the cellosaurus accession id the latter written as. Compounds are identified by the nci nsc number. Located at the national cancer institute in frederick maryland the dctd tumor repository.

These data are a subset of the data from the nci human tumor cell line screen. In the nci numbering system sk mel 28 is panel number 10 cell number 8. Activity score was based on increasing values of loggi50. In vivo derived tumors and.

In vitro established tumor cell lines from various species. These data are a subset of the data from the nci human tumor cell line screen. The division of cancer treatment and diagnosis dctd national cancer institute has maintained since the early 1960s a low temperature repository of transplantable. Links to corresponding cellosaurus descriptions and research resource identifiers rrid have been added.

Activity score was based on increasing values of loggi50. The national cancer institute nci has launched a national repository of patient derived models pdms comprised of patient derived xenografts pdxs and in vitro patient derived cell cultures pdcs including mixed cell populations clonal cell lines and fibroblast cell lines to serve as a resource for public private partnerships and for. Basically compounds with loggi50 unit m less than 6 were considered as active. These data are a subset of the data from the nci human tumor cell line screen.

This is a list of the 60 human cancer cell lines used in the screen and maintained at nci frederick. The nci 60 a panel of 60 diverse human cancer cell lines used by the developmental therapeutics program of the u s.